That is very important, since the way a protein in the body folds determines if a pharmaceutical will have the ability to bind to that protein and be efficient. In other words, we have to know how these proteins fold if we desire a drug to work. Historically, this has actually been a trial-and-error process (jeff brown biotech picks). Now, Alpha, Fold can predict protein folding with 92. 4% accuracy. That's going to make it much simpler to develop drugs that do what they're designed to do. This was a development practically nobody noticed. But it's going to have profound ramifications for treating disease. I predict that Alpha, Fold will be 98% precise by the end of 2021.
And, obviously, there will be a lot of investment opportunities in this area, too. Shifting topics It's going to be a good year for bitcoin. I'm bullish on it in 2021 (future report). That said, I still believe bitcoin will continue to be volatile. We're close to all-time highs. I would not be amazed if it drew back perhaps considerably prior to going higher - jeff brown latest prediction. I have actually been covering bitcoin for a long period of time now. Among the very first research study reports I ever published was on bitcoin. That was in June 2015. At the time, bitcoin was trading for about $240. Bitcoin trades for over $34,000 today.
But at the time of that preliminary recommendation, I titled my report "What's the Big Offer With Bitcoin?" That reveals you where the discussion was at the time. We were primarily educating readers. However that's not the big question any longer. Now we're seeing institutional cash lastly take an interest in bitcoin. Massachusetts Mutual Life Insurance took a $100 million stake in bitcoin in December. This is not some small, specific niche enterprise. Mass, Mutual is a relied on 170-year-old institution. So consider that. In 5 years, we went from informing readers on what bitcoin is to a company like Mass, Mutual taking a $100 million stake.
Which's a big factor I'm bullish on it this year. jeff brown genome sequencing. Regards, Jeff Brown, Editor, The Bleeding Edge I have a bonus offer forecast 2020 was a record year for IPOs. 552 U.S. business went public the most in more than twenty years. These companies raised an overall of $172 billion. That's an all-time high beating the previous annual record by 43%. I predict 2021 will be another record year in IPOs. There are many great personal companies on the brink of hitting the general public markets And I have actually been working on a brand-new method for you to invest even before these business go public.
This opportunity has been developing over the last few years. I can't wait to inform you everything about it. Join me tomorrow at 8 p. m. ET for my Pre-IPO Code Event to discover all the information. Go right here to schedule your area free of charge.
Emma Walsh here, handling editor of the Journal. Routine Journal readers understand that tech isn't our usual beat (diplomatic relations). And when it concerns tech investing, we leave it to the specialists. The good news is, we have several such specialists in our Rolodex. Our colleague Jeff Brown will be familiar to our long time readers. He is among the most accomplished tech investing specialists we know (tech stock). In fact, he had several triple-digit returns in his Brownstone Research portfolios last year. Here's what Jeff thinks the tech sector will bring us in 2021 Each year, I like to take an appearance at the big image and predict what's simply around the corner.
That consists of things like 5G networks, biotech, expert system, and much more. These patterns are experiencing exponential growth and producing extraordinary chances for financiers. I wish to ensure all our readers are prepared for what's next. And with that in mind, let me draw the picture of what I see can be found in the next 12 months Our new 5G (fifth-generation) cordless networks are a subject I've been covering for years now. last year. But despite what many readers might think, this is a pattern that's just beginning. Although the COVID-19 pandemic interfered with supply chains last year, an excellent 250 million 5G-enabled gadgets were still offered.
And all of this ultimately led to Apple delaying the release of the 5G-enabled i, Phone 12 by two months (jeff brown biotech stock). Losing two months of manufacturing and sales actually impacts how lots of 5G gadgets are sold in the calendar year. When you consider all of that, selling 250 million systems is remarkable. More notably, the hold-ups brought on by the pandemic developed a lots of pent-up demand. Which demand is now going to be pressed into 2021. In fact, I anticipate that more than 500 million 5G devices will be delivered in 2021 - jeff brown genome sequencing. And that's not my only 5G forecast When I have actually discussed 5G in the past, I've described its 3 different stages.
In Stage 2, 5G gadgets go on sale. 5G phones and other products begin to reach consumers. And in Stage 3, 5G services begin to be provided (social media). That's when we start to see applications running on 5G networks. Think about things like enormous multiplayer games over a mobile phone. That's not possible with 4G. It will be with 5G. And my second 5G prediction for 2021 is that we will begin Phase 3 by this summer. This starts something of a virtuous cycle: A lot of people do not actually appreciate the innovation. But they will care if there are interesting applications that can just be accessed with a 5G phone.
That leads to more 5G apps being developed. In truth, 5G is going to open a suite of extraordinary applications: self-driving cars, the Internet of Things, robotic surgical treatment, and more. All of these innovations need 5G. The financial investment opportunities moving forward will be huge. Stepping far from 5G, the next essential technology I visualize in 2021 is CRISPR hereditary modifying. CRISPR represents "clustered routinely interspaced brief palindromic repeat." It's a mouthful. However it is among the most interesting developments in biotechnology. At a high level, CRISPR is an innovation that can modify our hereditary makeup as if it were software.
The program can crash or not work properly. CRISPR utilizes a comparable concept but with our genetic code. "Typos" in our genome can result in disease. CRISPR can fix these "typos." For many years, CRISPR was mainly a niche technology that wasn't well comprehended. And throughout that time, there were really just three business running in this space. But things are changing. CRISPR is no longer simply theoretical. We're seeing actual results. We're dealing with diseases and seeing that this innovation just works. And as a result, a "2nd crop" of early-stage CRISPR business is going public and providing incredible returns. This whole market is successfully a greenfield chance.
There's room for many business to exist in this area. white house. And there will be more. That's my forecast for CRISPR in 2021. I anticipate that 2 or three more genetic modifying business will hold their IPOs. Sticking to biotechnology, we are seeing remarkable things occurring at the convergence of biotech and expert system (AI). Google's AI subsidiary, Deep, Mind, simply announced at the end of 2020 that its newest Alpha, Fold software application can precisely anticipate the folding of a protein based exclusively on its amino acid series with 92. 4% accuracy. That is necessary since the way a protein in the body folds determines if a pharmaceutical will be able to bind to that protein and work.
Historically, this has actually been an experimental process. But now, Alpha, Fold can predict protein folding with 92. 4% precision. That's going to make it a lot easier to create drugs that do what they're created to do. And here's my next prediction. I anticipate that Alpha, Fold will be 98% accurate by the end of 2021. And we will see not just one but numerous drug treatments produced using this technology. This was one of those breakthroughs that practically no one observed. But it's going to have extensive implications for treating disease. And, obviously, there will be plenty of financial investment opportunities in this space, too.
It's going to be an excellent year for bitcoin. I'm bullish on it in 2021. That said, I still think bitcoin will continue to be volatile. We're close to all-time highs. I wouldn't be shocked if it drew back possibly considerably prior to going greater. I've been covering bitcoin for a long time now. Among the very first research study reports I ever published was on bitcoin - legacy report prediction. That remained in June 2015. At the time, bitcoin was trading for about $240. Bitcoin trades for over $40,000 today. So that's a 16,500%+ return on investment for anybody who followed my recommendation. But at the time of that preliminary recommendation, I entitled my report, "What's the Big Deal With Bitcoin?" That reveals you where the conversation was at the time.
But nobody is asking that question any longer. Now, we're seeing institutional money finally taking an interest in bitcoin. The huge news was that Massachusetts Mutual Life Insurance took a $100 million stake in bitcoin in December. This is not some small, specific niche enterprise. last year. Mass, Mutual is a 150-year-old institution. So consider that. In five years, we went from educating readers on what bitcoin is to a business like Mass, Mutual taking a $100 million stake. The institutional adoption of bitcoin will continue. Which's a huge factor why I'm bullish on it this year. Regards, Jeff Brown, Editor, The Bleeding Edge I have another reward prediction In 2021, we're going to have another record year in IPOs. One website reports that Jeff Brown deserves about $27. 5 million and declares the information is up to date as of February 2021, however we could not separately verify this claim. Given Jeff Brown's past, he likely has a considerable net worth, however we can't hammer down an accurate figure at this minute. Brown is best known for his sage-like ability to select winning technology stocks. He invested more than 25 years investigating innovation business like Qualcomm, NXP semiconductors, and Juniper Networks. Brown's extensive experience gives him an outstanding point of view on the marketplace. He's always on the hunt for new opportunities, and he shares a number of his best picks in the Near Future Report.
That's high appreciation, but it's not ridiculously reasoned. Brown has an outstanding track record as a stock-picker, and he effectively forecasted some of the biggest economic events of the previous 20 years. Although he does not appear to launch his picks to the public, the service's success is a direct sign of Brown's stock-picking prowess. Nobody on Wall Street gets it ideal each time, however Jeff Brown's precise forecasts have actually made him legions of dedicated followers. That states a lot about his capability. The Near Future Report is published by Brownstone Research, a prominent financial research publisher. Brownstone Research offers a number of research study services with a wide range of specializations - what is the legacy report predicting.
The business is also affiliated with Bonner & Partners, another well-respected research publisher - jeff brown. On its site, Brownstone says its mission is to provide retail financiers with professional-grade research: "For too long, the best financial investment research study has actually not been offered to individual investors. It has actually been typically booked for financial investment banks, hedge funds, personal equity, and high-net-worth clients. what is the legacy report predicting. The mission of Brownstone Research study is to make that sort of exclusive research study offered to any financiers aiming to gain an edge in the marketplaces. The objective is easy to provide distinct and lucrative investment research study found nowhere else." -Brownstone Research study site excerpt from the Jeff Brown is the creator of Brownstone Research, and he likewise works as the company's Chief Financial investment Expert.
With Brown directing the ship, Brownstone Research is a powerhouse publisher with lots to offer its customers. After decades of steady success at the helm of top-tier business like Tesla and Area, X, Elon Musk is a family name throughout most of America. If you understand even a bit about the marketplace, you know that he has a reputation as a King Midas of sorts. brownstone research. Whatever he touches turns to gold! Jeff is well aware of Elon Musk's executive prowess, so he always has an eye out for the Silicon Valley rock star's next move. This time, Jeff has an early lead on Elon's next huge task.
In fact, Brown believes S.A.V. last year. could be "the most significant pattern of the 2020s, and he's not alone. Check out these quotes from other popular S.A.V. bulls: Elon's next huge act will be weding two advanced innovations: expert system and electrical cars. Musk hopes the mix will help him establish the very first fully-autonomous, self-driving vehicles ever. It's absolutely nothing except the vehicle industry's Holy Grail. As you know, electric automobiles and self-driving vehicle stocks have actually been huge this year, but the Wall Street device has actually been huge on buzz without much tangible outcome. In spite of a drastic boost in competition over the previous couple of years, Brown still thinks Musk has the finest possibility of putting it all together.
tech could be the magic string that ties all of it together. S.A.V. represents Shared Autonomous Automobile, and it might be the future of transport. Basically, this innovation would permit you to lease your automobile as a self-governing, self-driving taxi when you're not utilizing it. You just get out of the cars and truck and press a button on an app that informs the car to "sign up with the fleet." Next thing you know, you're relaxing on your couch while your vehicle shuttles ride-sharers around town. Most importantly, you get to keep a substantial chunk of the earnings. It sounds outrageous, however it might be closed than you believe.